Serological screening test for infectious mononucleosis using papain-treated sheep erythrocytes.
نویسندگان
چکیده
A screening test for infectious mononucleosis is described, based on the fact that antibodies against sheep red cells remaining after absorption of the serum by papain-treated sheep red cells appear to be specific for the disease. The test appears to be more useful in diagnosis than classical absorption techniques and has the advantage of being specific while maintaining a high degree of sensitivity.
منابع مشابه
Horse agglutinins in infectious mononucleosis TABLE I HORSE AGGLUTININ TITRES OF SERA HAVING SHEEP AGGLUTININ TITRES OF 14 OR LOWER Horse RBC TBA
SYNOPSIS One hundred infectious mononucleosis and the same number of non-infectious mononucleosis sera were studied to evaluate the sensitivity and specificity of horse erythrocytes in the diagnosis of infectious mononucleosis. Titres of horse agglutinins in infectious mononucleosis sera ranged from 28 to 7,168 with a geometric mean of 550, whereas the corresponding sheep agglutinin titres rang...
متن کاملStudies of Incomplete Antibodies I. Effect of Papain on Red Cells
By KI sI IO AH0 AND CHARLES L. CHRISTIAN I HE TREATMENT of red cells with some proteolytic enzymes has proved to be a suitable technic for the detection of a variety of blood group antibodies which coat but do not agglutinate erythrocytes in physiologic saline. The mechanism of this enzyme effect is not well understood. There is evidence that the antibodies revealed by the enzyme technic are no...
متن کاملStudies of Incomplete Antibodies I. Effect of Papain on Red Cells
By KI sI IO AH0 AND CHARLES L. CHRISTIAN I HE TREATMENT of red cells with some proteolytic enzymes has proved to be a suitable technic for the detection of a variety of blood group antibodies which coat but do not agglutinate erythrocytes in physiologic saline. The mechanism of this enzyme effect is not well understood. There is evidence that the antibodies revealed by the enzyme technic are no...
متن کاملStudies of incomplete antibodies. 1. Effect of papain on red cells.
By KI sI IO AH0 AND CHARLES L. CHRISTIAN I HE TREATMENT of red cells with some proteolytic enzymes has proved to be a suitable technic for the detection of a variety of blood group antibodies which coat but do not agglutinate erythrocytes in physiologic saline. The mechanism of this enzyme effect is not well understood. There is evidence that the antibodies revealed by the enzyme technic are no...
متن کاملStudies of Incomplete Antibodies I. Effect of Papain on Red Cells
By KI sI IO AH0 AND CHARLES L. CHRISTIAN I HE TREATMENT of red cells with some proteolytic enzymes has proved to be a suitable technic for the detection of a variety of blood group antibodies which coat but do not agglutinate erythrocytes in physiologic saline. The mechanism of this enzyme effect is not well understood. There is evidence that the antibodies revealed by the enzyme technic are no...
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عنوان ژورنال:
- Journal of clinical pathology
دوره 19 4 شماره
صفحات -
تاریخ انتشار 1966